Large Capacity Freeze Dryer

Large Capacity Freeze Dryer

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Large Capacity Freeze Dryer
  • Large Capacity Freeze Dryer
Large Capacity Freeze Dryer
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Large Capacity Freeze Dryer

The QualiFD™ L Series is a floor-standing, large-capacity freeze dryer engineered for high-throughput laboratory lyophilization in pharmaceutical, life science, and food R&D environments. Featuring a versatile, modular design with five distinct configurations—including top-press and manifold options—it offers an expandable drying area of up to 0.27 m² and a 6 kg ice-capture capacity to handle workloads that exceed benchtop limits. Its integrated caster-wheel base and GLP-focused stainless steel construction ensure both mobility and regulatory compliance across shared laboratory zones.
  • Up To 0.27 Square Meter Area With 6kg Per 24h Capacity
  • Minus 60C Cold Trap With Options To Minus 110C
  • 7 Inch Touchscreen With USB Data Export
  • Integrated Casters For Mobile Lab Use

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Large Capacity Freeze Dryer – QualiFD™ L Series

The Large Capacity Freeze Dryer – QualiFD™ L Series is a floor-standing freeze dryer machine designed for high-throughput laboratory lyophilization where benchtop systems fall short. It supports applications across pharmaceuticals, life sciences, chemical analysis, and food processing labs that require expanded drying area and reliable daily processing capacity.

Built for flexibility, the system features integrated caster wheels for smooth relocation between lab zones, making it suitable for shared or multi-purpose environments. The integrated floor design supports consistent operation while offering an expandable drying area of up to 0.27 m² to meet increasing workload demands.

The cold trap and working surface are constructed from stainless steel to support efficient cleaning and long-term resistance to corrosion. Product-contact components are made from inert materials, aligning with GLP-focused laboratory practices.

A large cold-trap opening combined with a built-in pre-freeze function supports streamlined workflows without the need for a separate low-temperature freezer. The intuitive touchscreen controller provides real-time monitoring and data logging of cold trap temperature, sample temperature, and vacuum curves, helping maintain process visibility and documentation for each run.

Applications of QualiFD™ L Series Large Capacity Freeze Dryer

Pharmaceutical and Medical Research:
Freeze drying preserves APIs, excipients, and formulation trials that may degrade in solution. The top-press setup enables vial workflows, allowing vials to be stoppered under vacuum after drying. Logged process curves provide R&D teams with detailed cycle comparisons and documentation for consistent batch results.

Biology and Biotechnology:
The system supports lyophilization of biological samples and reagents for extended storage and easier transport. The ampoule-tube setup is optimized for microorganism preservation, including bacteria and fungi. With a larger-capacity platform, labs can process more samples per run while maintaining a controlled vacuum environment.

Chemistry and Materials Development:
Freeze drying allows gentle solvent removal for heat-sensitive compounds, suspensions, and porous materials. Manifold configurations support drying in multiple vessels simultaneously. Stainless steel cold traps and work surfaces simplify routine cleaning when working with common laboratory solvents.

Food and Ingredient R&D:
Ideal for pilot studies, freeze drying protects the texture, aroma, and composition of sensitive ingredients. The expanded tray area accommodates higher sample volumes for process development. Integrated mobility ensures a single unit can be shared efficiently across multiple R&D rooms or departments.

Standards and Compliance

The QualiFD™ L Series Large Capacity Freeze Dryer adheres to internationally recognized standards for safe and reliable laboratory operation:

  • ISO 13408-3: Aseptic processing, Part 3 – Lyophilization
  • ASTM E3250: Instrumentation best practices for pharmaceutical freeze drying
  • IEC 61010-1: General safety requirements for laboratory electrical equipment

These certifications ensure the system meets rigorous quality, safety, and operational guidelines for pharmaceutical, biotechnology, and research applications.

Key Features – QualiFD™ L Series Large Capacity Freeze Dryer

  • Integrated One-Piece Construction: Minimizes leak points and simplifies installation in laboratory environments.
  • GLP-Focused Design: Product-contact components made from inert materials suitable for regulatory-compliant lab work.
  • Stainless Steel Cold Trap and Work Surface: Enhances corrosion resistance and simplifies cleaning for routine use.
  • All-Stainless Venting Valve: Designed to minimize leak risk and support safer operation.
  • Pre-Freeze Workflow Support: Large cold-trap opening and pre-freezing functionality streamline sample preparation.
  • Optimized Gas Flow Control: Improves ice capture uniformity within the cold trap.
  • 7-Inch Touchscreen Controller: Displays real-time temperature, sample, and vacuum curves, with options to export for review, printing, and reporting.
  • Built-In Alarms and Protection Logic: Monitors runtime, temperature, and component status to ensure safe and reliable operation.
  • Electric Defrost Function: Reduces turnaround time between drying cycles.
  • Caster-Wheel Base: Facilitates easy relocation across shared laboratory spaces.

Freeze Drying Theory and Method

Freeze drying removes water or solvent from a frozen product by applying a vacuum, allowing ice to sublimate directly into vapor without melting. A standard lyophilization cycle involves three main stages:

  • Freezing: The product is frozen to form ice crystals, establishing the structure for controlled drying.
  • Primary Drying (Sublimation): Under low pressure, ice transitions to vapor. Chamber pressure and cold-trap temperature influence the sublimation rate and capture efficiency. Continuous sample temperature monitoring ensures the product remains below its thermal limits.
  • Secondary Drying (Desorption): Remaining bound moisture is reduced to achieve stable storage conditions.

Vapor is captured on the cold trap, and after the drying process, the chamber is safely vented to atmospheric pressure for product unloading and sealing. This controlled method preserves structure, activity, and quality of sensitive materials.

Large Capacity Freeze Dryer – QualiFD™ L Series Technical Specification

  • QualiFD™ L1 (Standard): 4–6 stainless trays for bulk materials (liquid, paste, solid).
  • QualiFD™ L2 (Top-Press): 3 trays with adjustable spacing; supports vial drying and vacuum stoppering after drying.
  • QualiFD™ L3 (Standard + Multiple Manifolds): tray drying plus external hanging bottle attachment for vials or wide-mouth bottles; attachment can be removed during use.
  • QualiFD™ L4 (Top-Press + Multiple Manifolds): combines top-press vial workflow with manifold capability.
  • QualiFD™ L5 (Ampoule Tube): 24 ampoule interfaces for microorganism preservation workflows.

Full technical parameters

Specification QualiFD™ L1 QualiFD™ L2 QualiFD™ L3 QualiFD™ L4 QualiFD™ L5
Configuration Standard Top-press Standard + multiple manifolds Top-press + multiple manifolds Ampoule tube
Freeze drying area 0.18 / 0.27 m² 0.09 m² 0.18 / 0.27 m² 0.09 m² —
Cold trap temperature ≤ -60 °C (optional ≤ -80 °C, ≤ -110 °C no-load)
Ultimate vacuum < 5 Pa (no-load)
Water capture capacity 6 kg/24 h
Material tray 240 mm, 4 layers (optional 6) 200 mm, 3 layers 240 mm, 4 layers (optional 6) 200 mm, 3 layers —
Overall power 1400 W
Main unit weight 105 kg
Dimensions (W×D×H) 630×580×970 mm + (445 drying chamber) 630×580×970 mm + (540 drying chamber) 630×580×970 mm + (445 drying chamber) 630×580×970 mm + (540 drying chamber) 630×580×970 mm + (440)
Loadable materials (10 mm thickness reference) 1.8 / 2.7 L 0.9 L 1.8 / 2.7 L 0.9 L —
Loadable vials (tray reference) Φ12: 615; Φ16: 345; Φ22: 183 Φ12: 615; Φ16: 345; Φ22: 183 — — —

Delivery time varies upon stock availability. Our standard dispatch and shipping times are generally within 1 week, however for some high demand items the delivery may be extended to 2-3 weeks. If you require these items urgently please contact us to check accurate stock availability and to organize faster shipping methods.

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Important Delivery Information

Delivery time varies upon stock availability. Our standard dispatch and shipping times are generally within 1 week, however for some high demand items the delivery may be extended to 2-3 weeks.

Need it urgently? Contact us here to check stock and organize faster shipping.

Orders:
Purchaser acknowledges that when placing an order on the Qualitest:

A. the placing of the order signifies the purchaser's assent to place said order at the Qualitest and that the order will be accepted by the successful processing of the order by Qualitest USA LC.
B. the purchaser typing their name when requested to do so by the Qualitest constitutes a signature to contract
C. the purchaser has the full authority to enter into the contract for such entity, and such grant of authority was indicated by purchaser by placement of the order through the Qualitest.
D. A minimum handling fee will be applied to the shipping total for all orders.

Shipping within the U.S.A.:

All orders will be shipped best way prepaid, via courier for smaller packages or via Freight forwarders for larger crates. A handling fee may be applicable to orders. Title to merchandise transfers to the purchaser upon delivery to the carrier. Loss or damage in transit is the responsibility of the purchaser. Qualitest USA will provide assistance with information needed for processing claims.

Shipping outside of the U.S.A.:

All orders will be shipped best way, via courier for smaller packages or via Freight forwarders for larger crates. A low handling fee may be applicable. Title to merchandise transfers to the purchaser upon delivery to the carrier. Loss or damage in transit is the responsibility of the purchaser. Qualitest USA will provide assistance with information needed for processing claims. Export fees, duties, taxes, and customs clearance are the responsibility of the purchaser.

Shipping insurance is not included, please contact our sales representatives if you need shipping insurance.

Partial shipment: Qualitest USA reserves the right to make partial shipments unless otherwise instructed by the purchaser.

Payment terms: All payments to Qualitest USA are to be made in U.S. Dollars (USD)

A. Credit Card - Qualitest USA will accept Visa, Master Card, AMEX or Discover. Required information from the purchaser is the credit card number, 3 digit security code, expiration date, card holder's name (exactly as it appears on the card), billing address, and valid telephone number for us to use in case of difficulty. Qualitest USA reserves the right to delay shipment pending verification of credit card validity.
B. Wire Transfer - Transfer must be made to Qualitest and confirmed for the full purchase amount (merchandise, handling and shipping) prior to shipment. Please contact us by phone at 1.877.884.TEST (8378)(outside U.S. +1.905.944.9825) or by fax at +1.954.697.8211 for bank information.
C. Open Account - Available to U.S.A. and Canadian customers only. Terms on open accounts are Net 30 days from date of shipment. Qualitest USA reserves the right to refuse shipment of new orders if any unpaid invoices are older than 30 days. Purchasers may apply for an open account by providing:

their bank information
3 credit references from other suppliers
Please allow 5 business days for confirmation of credit and creation of an open account.

Return Policy:

Qualitest USA may accept return of purchased merchandise within North America for refund or credit under the following conditions -

  • There may be an additional restocking fee charged to the transaction if items are already shipped to customer.
  • Goods must be returned to Qualitest USA within 5 days of the date of the receipt of the purchased goods.
  • All freight, duties, customs, and other related shipping charges for the returned merchandise are borne by the purchaser. Shipments made freight collect will be refused.
  • Merchandise must be returned properly packaged in brand new, salable condition, along with original packaging and all documentation, accessories and certificates.
  • Purchaser has confirmed return authorization directly with Qualitest.
  • Merchandise is regular catalog item. Special order items can not be returned.
  • All returned merchandise is subject to inspection by Qualitest. Qualitest reserves the right to refuse return of any merchandise that is used, damaged, or not part of the current published price list. In the case Qualitest does not accept the returned merchandise, reasonable attempts will be made to notify the Buyer and the merchandise will be returned to Buyer as they were received by Qualitest. Damaged merchandise that can be restored to original condition and thus accepted for return will be evaluated on an individual basis. The purchaser will be advised of additional expenses for the repair and restoration of the returned item. After approval, these expenses will be charged to the purchaser in addition to the restocking fee.


Change of Terms:

The acceptance of any order by Qualitest USA is subject to purchaser's assent to all of the terms and conditions set forth herein. Purchaser's assent to these terms and conditions shall be presumed from the purchaser's placement of an order through the Qualitest. Any and all other terms and conditions are expressly rejected, and no addition or modification of terms and conditions shall be binding without the prior agreement of Qualitest USA in writing.

Complete Agreement:

The terms and conditions in the Qualitest web site, incorporated herein by reference, including forms, acknowledgements, quotations, invoices and sales terms and conditions constitute the entire and exclusive agreement between the purchaser and Qualitest USA LC.

Information:

Qualitest USA makes every effort to insure the accuracy of the product information displayed on its web sites, but makes no warranties, expressed or implied, as to the accuracy of the data portrayed on the web sites. Qualitest USA reserves the right to change product information, including pricing information at any time without notice. 

Trademarks and Copyrights:

The WorldofTest.com Qualitest contains trademarked product names. Product names are not to be reproduced or used in any fashion by any party other than Qualitest without the express written consent of Qualitest International Inc.. All pictures, descriptions, and other content of this web site are copyrighted by Qualitest USA and may not be used without the express written permission of Qualitest USA. Purchaser acknowledges that they have no right, title, or interest in the trademarks or copyrights in the products, and purchaser covenants that it will take no action to register or otherwise interfere with such rights. Please contact us with any requests for permission or questions about our trademarks. 

Warranty Disclaimer:

No warranty or affirmation of fact, express or implied, other than expressly set forth herein is made or authorized by Qualitest USA. Qualitest USA disclaims any and all liability for product defect claims. Qualitest USA does not express or imply a warranty that any product on the web site(s) is fit for a particular purpose. Qualitest USA honors the product warranty as published and made available by Qualitest USA. Warranty claims for products not manufactured by Qualitest are the responsibility of the manufacturer. Qualitest USA will always make its best good faith effort to resolve warranty claims. 


Force Majeure:

Qualitest USA shall not be liable for any delay in or impairment of performance resulting in whole or in part from Acts of God, service interruptions, labor disruptions, insurrections, governmental decrees or controls, war risks, severe weather, supplies or raw materials, inability to procure or ship products, inability to obtain permits and/or licenses, or any other circumstances or causes beyond the control of Qualitest USA in the conduct of its business. 

Qualitest USA Privacy Policy 

I. What legal provisions govern our data processing practices? How and from where (internal/external sources) is personal data acquired? What are the rights of the user (web site visitor/registered customer)? 

1. General
As a general principle, no personal details need to be provided when visiting our Internet site. Data made available to us by you is treated in strict confidence and in accordance with the provisions of the Federal Data Protection Act. With a few exceptions (see point 2 below), our web server only registers non-personal (anonymous) data concerning the use of our site. Specifically, the log files of our web server, as a general rule, only contain the user's IP address, the last page visited by the user, the browser used, date, time and the file requested. This anonymous data, however, does not permit conclusions to be drawn about the individual users, and merely serves to prepare statistics on the use of our Internet site for the purpose of its improvement. At the same time, great importance is placed on ensuring that usage data is not linked with personal data. 

2. Personal data

Person-related data (personal data) is only used if the newsletter is ordered (by email), product(s) is (are) ordered, or to supply product information. We undertake to use the personal data entrusted to us only for the purposes stated. Purchase history is retained for assistance with future customer needs. 

II. What security measures are used to protect personal data? What are the user's options for processing personal data? 

3. Technical measures

Databases are optimally protected against third party access, loss, misuse and falsification through the use of appropriate technical means. In order to determine the popularity of individual topic areas, cookies are used in those sections. These text files are stored on your hard disk and facilitate your use of our Internet site. Thanks to these cookies, there is no need for specific registration each time you visit a section requiring registration, and we can supply you with the personalized contents you request. 

It is for you to decide whether you want to work with cookies and, if so, which kind (permanently stored on the hard disk or only placed for the time of the browser activity). However, we draw your attention to the fact that access to fields requiring registration is only possible with activated cookies. 

III. What data is communicated to third parties and for what purposes? 

4. Communication of personal data

Personal data entrusted to us by you is not communicated, leased or sold to third parties. 

IV. Which department answers questions about the processing of personal data? 

5. Contact

In the light of the rapid technical developments in connection with the Internet, we make every effort to constantly improve our Internet site and technical precautions, including those connected with data protection. We will keep you suitably informed about such measures. Any changes will be published here. Further information is available at any time by contacting Qualitest USA.

Disclaimer of liability Qualitest USA shall not be liable for direct, indirect or consequential losses resulting from or in connection with access to, use of or queries to the Qualitest web site or its links with other web sites, even if Qualitest USA has previously been informed of the possibility of such losses. No guarantee is provided as to the accuracy of the information disseminated via the Qualitest USA web site. In addition, Qualitest USA guarantees neither the reliability nor the completeness of the information contained on its web site. The information made available on the Qualitest and WorldofTest.com web site may be amended at any time without prior notice. In particular, Qualitest USA shall not be liable for losses caused by transmission errors, technical faults and interruptions, breakdowns or an unlawful interference with the user's data processing system or the generally accessible systems and transmission networks. Nor shall Qualitest USA be liable for losses resulting from breakdowns, interruptions or overloads occurring to any data processing systems. If certain links are activated on the Qualitest and WorldofTest.com web site, the user may under certain circumstances leave the Qualitest web site. Qualitest USA assumes no responsibility for the contents, products or services offered or other information or offers contained on these linked web sites. 

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