{"product_id":"small-r-d-freeze-dryer","title":"Small R\u0026D Freeze Dryer","description":"\u003ch2\u003eSmall R\u0026amp;D Freeze Dryer – QualiRFD™ 6\u003c\/h2\u003e\n\u003cp\u003eThe QualiRFD™ 6 Small R\u0026amp;D Freeze Dryer is built to replicate production-level freeze-drying performance in a compact, pilot-scale format. It enables accurate parameter development, method refinement, and reliable scale-up by maintaining process conditions aligned with full-scale systems.\u003c\/p\u003e\n\u003cp\u003eDesigned for advanced freeze-drying research, QualiRFD™ 6 helps maintain critical product temperature limits and key transition points throughout the cycle. It fits seamlessly into early-stage development, process validation, and scale-up workflows where consistency with production conditions is essential.\u003c\/p\u003e\n\u003cp\u003eThe system features a PLC-driven control platform with a dedicated interface for consistent and repeatable operation. It supports cycle programming, recipe storage, real-time data logging, process curve visualization, and detailed reporting—helping labs maintain control, traceability, and process accuracy across R\u0026amp;D activities.\u003c\/p\u003e\n\u003ch2\u003eSmall R\u0026amp;D Freeze Dryer – QualiRFD™ 6 Applications\u003c\/h2\u003e\n\u003cp\u003ePharmaceutical and Biotech Process Development: The QualiRFD™ 6 provides precise shelf temperature control and stable vacuum conditions essential for sensitive formulations. It is ideal for refining freeze-drying cycles before transitioning to larger manufacturing-scale equipment.\u003c\/p\u003e\n\u003cp\u003eLife Sciences and Specialty Materials: Some samples require extremely low critical temperatures and careful control during pre-freezing and sublimation. QualiRFD™ 6 delivers the control range needed for specialized freeze-drying applications beyond what standard lab units can achieve.\u003c\/p\u003e\n\u003cp\u003eScale-Up and Process Amplification: This pilot-scale freeze dryer bridges bench research and production by maintaining process characteristics comparable to full-scale systems. It is suitable for scaling up experiments and closely matching production-level parameters.\u003c\/p\u003e\n\u003cp\u003eUniformity and Process Repeatability: Consistent drying across trays is critical for validating recipes and comparing batches. QualiRFD™ 6 ensures uniform results through its tray and cold-trap design, combined with stable process control, supporting repeatable and reliable R\u0026amp;D outcomes.\u003c\/p\u003e\n\u003ch3\u003eStandards Compliance – QualiRFD™ 6\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eISO 13408-3: Provides requirements and guidance for performing lyophilization as an aseptic process, applicable to healthcare products.\u003c\/li\u003e\n\u003cli\u003eASTM E3250: Establishes best practices for freeze dryer instrumentation, focusing on accurate product temperature and pressure measurement.\u003c\/li\u003e\n\u003cli\u003eIEC 61010-1: Covers general safety requirements for electrical laboratory and process-control equipment, ensuring safe operation and compliance.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eSmall R\u0026amp;D Freeze Dryer – QualiRFD™ 6 Key Features\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePilot-Scale Design: Engineered to replicate production freeze-dryer performance, enabling accurate parameter optimization and scale-up studies.\u003c\/li\u003e\n\u003cli\u003ePLC-Based Control System: Ensures consistent, repeatable process execution for reliable batch-to-batch performance.\u003c\/li\u003e\n\u003cli\u003eAdvanced Program Management: Supports recipe storage, real-time process monitoring, curve generation, detailed reporting, alarms, and historical record keeping.\u003c\/li\u003e\n\u003cli\u003eOptimized Tray Thermal Design: Promotes uniform heat distribution across shelves to improve drying consistency.\u003c\/li\u003e\n\u003cli\u003eHigh-Quality Product-Contact Materials: Stainless steel construction with internal components designed for easy cleaning and maintenance.\u003c\/li\u003e\n\u003cli\u003eGMP-Aligned Control System: Positioned to meet GMP and 21 CFR Part 11-style requirements, with optional remote-control capabilities.\u003c\/li\u003e\n\u003cli\u003eOptional Advanced Functions: Includes features such as vacuum level control, eutectic point testing, and chamber isolation valves for in-depth process studies.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eTheory and Method – QualiRFD™ 6\u003c\/h2\u003e\n\u003cp\u003eFreeze drying removes solvents by first freezing the product, then applying a vacuum so ice converts directly to vapor through sublimation. Controlled shelf temperature and chamber pressure manage heat and mass transfer during primary drying, followed by secondary drying to reduce residual moisture under precise conditions.\u003c\/p\u003e\n\u003cp\u003eThe QualiRFD™ 6 enables program-driven operation with multi-stage temperature control and recorded cycle curves, allowing R\u0026amp;D teams to analyze runs, compare performance, and fine-tune process setpoints for reliable development results.\u003c\/p\u003e\n\u003ch2\u003eSmall R\u0026amp;D Freeze Dryer – QualiRFD™ 6 Technical Specification\u003c\/h2\u003e\n\u003ctable class=\"table\" border=\"1\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eSpecification\u003c\/th\u003e\n\u003cth\u003eQualiRFD™ 6\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eFreeze drying area\u003c\/td\u003e\n\u003ctd\u003e0.3 m²\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCold trap temperature\u003c\/td\u003e\n\u003ctd\u003e\u0026lt; -75 °C (no-load)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVacuum level\u003c\/td\u003e\n\u003ctd\u003e≤ 1 Pa (no-load)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eShelf temperature range\u003c\/td\u003e\n\u003ctd\u003e-55 to +70 °C (no-load)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMaximum ice capacity\u003c\/td\u003e\n\u003ctd\u003e≥ 6 kg\/24 h\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eNumber of shelf layers\u003c\/td\u003e\n\u003ctd\u003e3 + 1\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMaterial tray size\u003c\/td\u003e\n\u003ctd\u003e400 × 270 mm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eShelf spacing\u003c\/td\u003e\n\u003ctd\u003e70 mm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOverall power\u003c\/td\u003e\n\u003ctd\u003e3 kW\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eWeight\u003c\/td\u003e\n\u003ctd\u003e300 kg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDimensions (W×D×H)\u003c\/td\u003e\n\u003ctd\u003e1033 × 781 × 1580 mm\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eLoadable materials\u003c\/td\u003e\n\u003ctd\u003e3 L\/kg\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDefrost mode\u003c\/td\u003e\n\u003ctd\u003eElectric defrost\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSafety devices\u003c\/td\u003e\n\u003ctd\u003eAudible alarm, emergency stop switch, overpressure protection\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eVoltage\u003c\/td\u003e\n\u003ctd\u003eSingle-phase 3-wire, 220 V (110V is also available)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOptional features (selected)\u003c\/td\u003e\n\u003ctd\u003eVacuum level control; eutectic point testing; chamber isolation valve; PC\/mobile remote control; imported vacuum pumps; anti-oil backflow solenoid valve; oil mist filter\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"Qualitest USA LC","offers":[{"title":"Default Title","offer_id":51846856016183,"sku":null,"price":100.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0786\/1859\/1543\/files\/small-rd-freeze-dryer1487096390.webp?v=1775039457","url":"https:\/\/qualitest.us\/ar\/products\/small-r-d-freeze-dryer","provider":"Qualitest USA LC","version":"1.0","type":"link"}